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Text File  |  1987-10-07  |  580b  |  15 lines
  1.  
  2.          IN PATIENTS WITH RENAL IMPAIRMENT, DIFLUNISAL DOSAGE SHOULD
  3.          BE CAREFULLY ADJUSTED TO AVOID TOXICITY (WORSENING OF RENAL
  4.          FUNCTION, NEPHROTIC SYNDROME, INTERSTITIAL NEPHRITIS).
  5.           
  6.          SOME CLINICIANS RECOMMEND THAT THE DOSAGE REGIMEN BE
  7.          ADJUSTED BASED ON THE PATIENT'S CREATININE CLEARANCE:
  8.           
  9.                  CREATININE            DOSAGE REDUCTION
  10.                   CLEARANCE                 METHOD
  11.                  (ML/MINUTE)
  12.           
  13.                      <10               50% of normal dose
  14.           
  15.